Clinical Pathways

This clinical algorithm provides step-by-step guidance for the recognition, stabilization, and treatment of pediatric status epilepticus in the emergency department. Developed through the EIIC PEAK initiative, it supports rapid decision-making, medication selection, and escalation of care to promote timely, standardized management of this life-threatening condition.

This algorithm guides emergency department teams in the assessment and management of the agitated pediatric patient. Developed in collaboration with EIIC and TREKK, it emphasizes safety, de-escalation strategies, appropriate medication use, and trauma-informed care to support effective, compassionate management of behavioral emergencies.

This pathway outlines best practices for the initial evaluation and stabilization of pediatric patients with multisystem trauma. It highlights key clinical priorities, resuscitation principles, and factors influencing trauma triage and transfer decisions, supporting consistent, high-quality care during the critical early phase of trauma management.

This clinical resource provides guidance for the recognition and management of pediatric hemorrhagic shock, including implementation of massive transfusion protocols. It emphasizes rapid assessment, balanced resuscitation, and coordinated blood product administration to improve outcomes and standardize trauma care.

This algorithm outlines key management strategies for the resuscitation of children with traumatic brain injury. It focuses on early recognition, physiologic stabilization, and prevention of secondary brain injury, supporting ED teams in delivering timely, evidence-based care.

This pathway consolidates national guidelines and expert recommendations to support evidence-based imaging decisions in pediatric trauma. It addresses imaging for head, cervical spine, thoracic, and abdominal injuries, balancing diagnostic accuracy with radiation safety and clinical need.

This clinical pathway from Children’s Hospital of Philadelphia (CHOP) provides structured guidance for the early identification and management of pediatric sepsis across emergency, inpatient, and PICU settings. It emphasizes rapid recognition, timely antibiotics, fluid resuscitation, and escalation of care to improve outcomes.

This clinical pathway from UH Rainbow Babies & Children’s Hospital provides evidence-based management of bronchiolitis in the emergency department, including indications for high-flow nasal cannula therapy. It supports standardized assessment, respiratory support decisions, and disposition planning for infants and young children.